The PDCD1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD279, hPD-1, PD-1, PD1, and PDCD1. This antibody recognizes Human antigen. The PDCD1 Antibody has been validated for the following applications: Immunohistochemistry.
Description
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases